High-performance non-enzymatic electrochemical sensing of glucose: Using tailored CuS/CoS2 nanocomposite

초록

Accurate glucose detection in beverages is critical for dietary monitoring and public health management, as excessive sugar consumption is strongly linked to diabetes, obesity, cardiovascular disorders, and cancer. Herein, a CuS/CoS<inf>2</inf> nanocomposite was synthesized via a facile ultrasonication-assisted strategy and used to fabricate a modified electrode for non-enzymatic glucose sensing. The CuS/CoS<inf>2</inf> sensor, after optimization, demonstrated a broad linear detection range from 100 μM to 12 mM. It delivered a remarkable sensitivity of 736.05 μA mM−1 cm−2 and achieved an impressively low detection limit of 0.35 μM, exceeding the performance of conventional enzyme-based sensing systems. Moreover, real-sample validation using commercial beverages Coca-Cola, Black Tea, and Sprite yielded recovery rates of 96.42% to 102.63% and relative standard deviation (RSD) values below 1.14%, demonstrating high accuracy, reproducibility, and resilience in complex matrices. These findings highlight the CuS/CoS<inf>2</inf> nanocomposite as a robust, non-enzymatic platform for glucose quantification in liquid food samples, offering significant potential to advance dietary surveillance and mitigate sugar-related health risks through precise analytical and healthcare applications. © 2026 Elsevier B.V.

키워드