Novel Xylene-Linked Maltoside Amphiphiles (XMAs) for Membrane Protein Stabilisation

Cho, Kyung Ho; Du, Yang; Scull, Nicola J.; Hariharan, Parameswaran; Gotfryd, Kamil; Loland, Claus J.; Guan, Lan; Byrne, Bernadette; Kobilka, Brian K.; Chae, Pil Seok

doi:10.1002/chem.201501083

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Novel Xylene-Linked Maltoside Amphiphiles (XMAs) for Membrane Protein Stabilisation

Cho, Kyung Ho;
Du, Yang;
Scull, Nicola J.;
Hariharan, Parameswaran;
Gotfryd, Kamil;
... Chae, Pil Seok;
외 4명

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초록

ThisworkwassupportedbytheNationalResearchFoundationofKorea(NRF)fundedbytheKoreanGovernment(MSIP;grantnumbers2008-0061891and2013R1A2A2A03067623toP. S.C.andK.H.C.).TheworkwasalsosupportedbyBiotechnologyandBiologicalSciencesResearchCouncilgrantBB/K017292/1toB.B.N.J.S.istherecipientofaBBSRCdoctoraltrainingpro-grammestudentshipawardedtoB.B.ThisworkwassupportedbytheNationalScienceFoundation(grantMCB-1158085toL.G.)andbytheNationalInstitutesofHealth(grantR01GM095538toL.G.).C.J.L.isfundedbytheDanishCouncilforIndependentResearchSapereAudeprogram,TheCarlsbergFoundationandtheUNIKcenterforSyntheticBiology.

키워드

amphiphile design; membrane proteins; detergents; protein stabilisation; protein structure; GLYCOL GNG AMPHIPHILES; CRYSTAL-STRUCTURE; FACIAL AMPHIPHILES; MNG AMPHIPHILES; RECEPTOR; SOLUBILIZATION; CRYSTALLIZATION; CRYSTALLOGRAPHY; STABILITY; INSIGHTS

제목: Novel Xylene-Linked Maltoside Amphiphiles (XMAs) for Membrane Protein Stabilisation

저자: Cho, Kyung Ho; Du, Yang; Scull, Nicola J.; Hariharan, Parameswaran; Gotfryd, Kamil; Loland, Claus J.; Guan, Lan; Byrne, Bernadette; Kobilka, Brian K.; Chae, Pil Seok

DOI: 10.1002/chem.201501083

발행일: 2015-07

유형: Article

저널명: Chemistry - A European Journal

권: 21

호: 28

페이지: 10008 ~ 10013

언어: ENG

출판사: WILEY-V C H VERLAG GMBH

발행국가: 독일

분량: 6 페이지

ISSN: E 1521-3765
P 0947-6539