New synthetic route to N-tocopherol derivatives: synthesis of pyrrolopyridinol analogue of alpha-tocopherol from pyridoxine

  • Nam, Tae-gyu; 
  • Ku, Jin-Mo; 
  • Park, Hyeung-geun; 
  • Porter, Ned A.; 
  • Jeong, Byeong-Seon
Citations

WEB OF SCIENCE

14
Citations

SCOPUS

15

초록

A new synthetic route to pyrrolopyridinol antioxidants from easily accessible pyridoxine was developed which includes phase-transfer catalytic alkylation and intramolecular Cu(I)-catalyzed amination as key steps.

키워드

pyridine derivative; chemistry; synthesis; Pyridines; Phase-transfer catalytic alkylation; Synthetic routes; Hydroxylation; hydroxylation; Stereoisomerism; Pyrroles; alpha tocopherol; alpha-Tocopherol; Pyridoxine; article; pyridoxine; stereoisomerism; pyr; CHAIN-BREAKING ANTIOXIDANTS; PHASE-TRANSFER CATALYSTS; 6-AMINO-3-PYRIDINOLS; 5-PYRIMIDINOLS; REACTIVITY
제목
New synthetic route to N-tocopherol derivatives: synthesis of pyrrolopyridinol analogue of alpha-tocopherol from pyridoxine
저자
Nam, Tae-gyu; Ku, Jin-Mo; Park, Hyeung-geun; Porter, Ned A.; Jeong, Byeong-Seon
DOI
10.1039/c0ob00991a
발행일
2011-03
유형
Article
저널명
Organic & Biomolecular Chemistry
권
9
호
6
페이지
1749 ~ 1755