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Peptide-cleaving catalyst selective for peptide deformylase
- Chae, Pil-seok;
- Kim, Myoungsoon;
- Jeung, Chul-seung;
- Lee,Seongdu;
- Park, Hwangseo;
- 외 2명
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63초록
A peptide-cleaving catalyst selective for peptide deformylase (PDF) was obtained from a library containing about 15000 catalyst candidates. The catalyst cleaved the polypeptide backbone of PDF at Gln(152)-Arg(153). Docking simulations suggested multiple modes of interactions in the complex formed between the catalyst and PDF. Copyright © 2005 American Chemical Society.
키워드
ARTIFICIAL PROTEASE; HYDROLYSIS; COMPLEX; ION
- 제목
- Peptide-cleaving catalyst selective for peptide deformylase
- 저자
- Chae, Pil-seok; Kim, Myoungsoon; Jeung, Chul-seung; Lee,Seongdu; Park, Hwangseo; Lee, Sangyoub; Suh, Junghun
- 발행일
- 2005-03
- 유형
- Article
- 권
- 127
- 호
- 8
- 페이지
- 2396 ~ 2397
- 언어
- ENG
- 출판사
- AMER CHEMICAL SOC
- 발행국가
- 미국
- 분량
- 2 페이지
- ISSN
- E 1520-5126
P 0002-7863