Identification of Novel Acetylenic Alcohols and a New Dihydrothiopyranone from the Tropical Sponge Reniochalina sp.

  • Lee, Hyi-Seung; 
  • Lee, Ji Hye; 
  • Won, Hoshik; 
  • Park, Song-Kyu; 
  • Kim, Hwan Mook; 
  • 외 4명
Citations

WEB OF SCIENCE

13
Citations

SCOPUS

15

초록

Two new acetylenic alcohols (1-2) and a new dihydrothiopyranone (3) were isolated from the tropical sponge Reniochalina sp. Their structures were determined by spectroscopic and chemical methods to be (3R)-hydroxyoctatriacont-(4E)-en-1-yne (1), 5-hydroxyheptatriacont-(3Z)-en-1-yne (2) and 2-hexadecyl-2,3-dihydrothiopyran-4-one (3). The acetylenic alcohol (1) exhibited significant growth inhibitory effect against human tumor cell lines.

키워드

Tropical sponge; Reniochalina sp.; Acetylenic alcohol; Dihydrothiopyranone; Growth inhibition; OKINAWAN MARINE SPONGE; CYTOTOXIC POLYACETYLENES; CRIBROCHALINA-VASCULUM; PETROSIA; STEREOCHEMISTRY; STRONGYLOPHORA; LIPIDS; ACID
제목
Identification of Novel Acetylenic Alcohols and a New Dihydrothiopyranone from the Tropical Sponge Reniochalina sp.
저자
Lee, Hyi-Seung; Lee, Ji Hye; Won, Hoshik; Park, Song-Kyu; Kim, Hwan Mook; Shin, Hee Jae; Park, Heung Sik; Sim, Chung J.; Kim, Hye-Kyeong
DOI
10.1007/s11745-008-3249-3
발행일
2009-01
유형
Article
저널명
Lipids
권
44
호
1
페이지
71 ~ 75