Recent Development of Inorganic Nanoparticles for Biomedical Imaging

  • Kim, Dokyoon; 
  • Kim, Jonghoon; 
  • Park, Yong Il; 
  • Lee, Nohyun; 
  • Hyeon, Taeghwan
Citations

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266

초록

Inorganic nanoparticle-based biomedical imaging probes have been studied extensively as a potential alternative to conventional molecular imaging probes. Not only can they provide better imaging performance but they can also offer greater versatility of multimodal, stimuli-responsive, and targeted imaging. However, inorganic nanoparticle-based probes are still far from practical use in clinics due to safety concerns and less-optimized efficiency. In this context, it would be valuable to look over the underlying issues. This outlook highlights the recent advances in the development of inorganic nanoparticle-based probes for MRI, CT, and anti-Stokes shift-based optical imaging. Various issues and possibilities regarding the construction of imaging probes are discussed, and future research directions are suggested.

키워드

UP-CONVERSION NANOPARTICLES; IRON-OXIDE NANOPARTICLES; LARGE-SCALE SYNTHESIS; MRI CONTRAST AGENTS; DOPED UPCONVERTING NANOPARTICLES; COATED GOLD NANOPARTICLES; IN-VIVO BIODISTRIBUTION; COMPUTED-TOMOGRAPHY; QUANTUM DOTS; MAGNETIC NANOPARTICLES
제목
Recent Development of Inorganic Nanoparticles for Biomedical Imaging
저자
Kim, Dokyoon; Kim, Jonghoon; Park, Yong Il; Lee, Nohyun; Hyeon, Taeghwan
DOI
10.1021/acscentsci.7b00574
발행일
2018-03
유형
Article
저널명
ACS CENTRAL SCIENCE
권
4
호
3
페이지
324 ~ 336