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Smart chemistry-based nanosized drug delivery systems for systemic applications: A comprehensive review
- Ramasamy, Thiruganesh;
- Ruttala, Hima Bindu;
- Gupta, Biki;
- Poudel, Bijay Kumar;
- Choi, Han-Gon;
- 외 2명
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WEB OF SCIENCE
336Citations
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358초록
This review focuses on the smart chemistry that has been utilized in developing polymer-based drug delivery systems over the past 10 years. We provide a comprehensive overview of the different functional moieties and reducible linkages exploited in these systems, and outline their design, synthesis, and application from a therapeutic efficacy viewpoint. Furthermore, we highlight the next generation nanomedicine strategies based on this novel chemistry.
키워드
Nanomedicine; Smart chemistry; Nanocarrier; Drug delivery; CROSS-LINKED MICELLES; MESOPOROUS SILICA NANOPARTICLES; REDUCTION-SENSITIVE MICELLES; RING-OPENING POLYMERIZATION; BLOCK-COPOLYMER MICELLES; POLYELECTROLYTE COMPLEX MICELLES; ENZYME-RESPONSIVE NANOPARTICLES; HISTONE DEACETYLASE INHIBITOR; TARGETED INTRACELLULAR DRUG; SELF-IMMOLATIVE POLYMERS
- 제목
- Smart chemistry-based nanosized drug delivery systems for systemic applications: A comprehensive review
- 저자
- Ramasamy, Thiruganesh; Ruttala, Hima Bindu; Gupta, Biki; Poudel, Bijay Kumar; Choi, Han-Gon; Yong, Chul Soon; Kim, Jong Oh
- 발행일
- 2017-07
- 유형
- Review
- 권
- 258
- 페이지
- 226 ~ 253
- 언어
- ENG
- 출판사
- ELSEVIER SCIENCE BV
- 발행국가
- 네덜란드
- 분량
- 28 페이지
- ISSN
- E 1873-4995
P 0168-3659