Bio-interfacial magnetic resonance imaging of hyperpolarized contrast agents for metabolic flux interrogation in vivo

Jeong, Gijin; Lee, Jee-Wook; Gong, Gyeonghyeon; Ko, Hyeji; Choi, Ikjang; Seo, Hyeonglim; Lee, Youngbok; Millward, Niki M. Zacharias; Bhattacharya, Pratip K.

doi:10.1016/j.jiec.2016.02.002

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Bio-interfacial magnetic resonance imaging of hyperpolarized contrast agents for metabolic flux interrogation in vivo

Jeong, Gijin;
Lee, Jee-Wook;
Gong, Gyeonghyeon;
Ko, Hyeji;
Choi, Ikjang;
... Lee, Youngbok;
외 3명

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초록

We utilized dynamic nuclear polarization to hyperpolarize three metabolic imaging agents as single agents and together (co-polarization with two different organic radicals; OX63 and BDPA). In addition, we describe our initial two slice selective spectroscopy in vivo experiments in mice. These techniques along with advances by other laboratories will allow for multiple metabolic pathways to be imaged in real-time and in vivo. (C) 2016 The Korean Society of Industrial and Engineering Chemistry. Published by Elsevier B.V. All rights reserved.

키워드

Hyperpolarization; Dynamic nuclear polarization; MR spectroscopy and imaging; In vivo metabolic MR

제목: Bio-interfacial magnetic resonance imaging of hyperpolarized contrast agents for metabolic flux interrogation in vivo

저자: Jeong, Gijin; Lee, Jee-Wook; Gong, Gyeonghyeon; Ko, Hyeji; Choi, Ikjang; Seo, Hyeonglim; Lee, Youngbok; Millward, Niki M. Zacharias; Bhattacharya, Pratip K.

DOI: 10.1016/j.jiec.2016.02.002

발행일: 2016-04

유형: Article

저널명: Journal of Industrial and Engineering Chemistry

권: 36

페이지: 224 ~ 228

언어: ENG

출판사: ELSEVIER SCIENCE INC

발행국가: 미국

분량: 5 페이지

ISSN: E 1876-794X
P 1226-086X