CD28/B7 deficiency attenuates systolic overload-induced congestive heart failure, myocardial and pulmonary inflammation, and activated T cell accumulation in the heart and lungs

Wang, Huan; Kwak, Dong min; Fassett, John; Hou, Lei; Xu, Xin; Burbach, Brandon J.; Thenappan, Thenappan; Xu, Yawei; Ge, Jun-Bo; Shimizu, Yoji; Bache, Robert J.; Chen, Yingjie

doi:10.1161/HYPERTENSIONAHA.116.07579

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CD28/B7 deficiency attenuates systolic overload-induced congestive heart failure, myocardial and pulmonary inflammation, and activated T cell accumulation in the heart and lungs

Wang, Huan;
Kwak, Dong min;
Fassett, John;
Hou, Lei;
Xu, Xin;
외 7명

Citations

WEB OF SCIENCE

49

Citations

SCOPUS

54

초록

United States Department of Health & Human Services-United States Public Health Service[HL021872][HL098669][HL098719][HL102597][HL089249][R01HL105406];National Natural Science Foundation of China (NSFC)[81470512][81570355];United States Department of Health & Human Services-National Institutes of Health (NIH) - USA[T32HL069764];American Heart Association[09GRNT2260175];United States Department of Health & Human Services-National Institutes of Health (NIH) - USA-NIH National Cancer Institute (NCI)[P30CA077598];United States Department of Health & Human Services-National Institutes of Health (NIH) - USA-NIH National Heart Lung & Blood Institute (NHLBI)[R21HL098719][R01HL105406][T32HL069764][R01HL021872][R21HL102597][R01HL089249][R21HL098669]

키워드

congestive heart failure; heart; inflammation; leukocytes; lung; T-cell activation; abatacept; CD28 antigen; CD3 antigen; Hermes antigen; interleukin 1beta; tumor necrosis factor alpha; abatacept; B7 antigen; CD28 antigen; cytokine; animal cell; animal experiment; animal model; animal tissue; aorta constriction; Article; congestive heart failure; controlled study; heart left ventricle contractility; heart left ventricle failure; heart left ventricle hypertrophy; heart ventricle overload; heart weight; knockout mouse; lung weight; male; mouse; myocarditis; nonhuman; pneumonia; priority journal; protein deficiency; T lymphocyte activation; analysis of variance; animal; C57BL mouse; disease model; drug effects; heart failure; immunology; metabolism; nonparametric test; pathophysiology; physiology; pneumonia; randomization; systole; T lymphocyte; Abatacept; Analysis of Variance; Animals; Antigens, CD28; B7 Antigens; Cytokines; Disease Models, Animal; Heart Failure; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pneumonia; Random Allocation; Statistics, Nonparametric; Systole; T-Lymphocytes

제목: CD28/B7 deficiency attenuates systolic overload-induced congestive heart failure, myocardial and pulmonary inflammation, and activated T cell accumulation in the heart and lungs

저자: Wang, Huan; Kwak, Dong min; Fassett, John; Hou, Lei; Xu, Xin; Burbach, Brandon J.; Thenappan, Thenappan; Xu, Yawei; Ge, Jun-Bo; Shimizu, Yoji; Bache, Robert J.; Chen, Yingjie

DOI: 10.1161/HYPERTENSIONAHA.116.07579

발행일: 2016-09

유형: Article

저널명: Hypertension

권: 68

호: 3

페이지: 688 ~ 696

언어: ENG

출판사: Lippincott Williams & Wilkins Ltd.

발행국가: 미국

분량: 9 페이지

ISSN: E 1524-4563
P 0194-911X

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CD28/B7 deficiency attenuates systolic overload-induced congestive heart failure, myocardial and pulmonary inflammation, and activated T cell accumulation in the heart and lungs

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