Tandem Facial Amphiphiles for Membrane Protein Stabilization

  • Chae, Pil Seok; 
  • Gotfryd, Kamil; 
  • Pacyna, Jennifer; 
  • Miercke, Larry J. W.; 
  • Rasmussen, Soren G. F.; 
  • 외 8명
Citations

WEB OF SCIENCE

83
Citations

SCOPUS

86

초록

We describe a new type of synthetic amphiphile that is intended to support biochemical characterization of intrinsic membrane proteins. Members of this new family displayed favorable behavior with four of five membrane proteins tested, and these amphiphiles formed relatively small micelles.

키워드

DETERGENTS; STABILITY; BINDING
제목
Tandem Facial Amphiphiles for Membrane Protein Stabilization
저자
Chae, Pil Seok; Gotfryd, Kamil; Pacyna, Jennifer; Miercke, Larry J. W.; Rasmussen, Soren G. F.; Robbins, Rebecca A.; Rana, Rohini R.; Loland, Claus J.; Kobilka, Brian; Stroud, Robert; Byrne, Bernadette; Gether, Ulrik; Gellman, Samuel H.
DOI
10.1021/ja1072959
발행일
2010-12
유형
Article
저널명
Journal of the American Chemical Society
권
132
호
47
페이지
16750 ~ 16752