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A Concise Synthesis of Tetrabenazine: An Intramolecular Aza-Prins-Type Cyclization via Oxidative C-H Activation
- Son, Young Wook;
- Kwon, Tae Hui;
- Lee, Jae Kyun;
- Rae, Ae Nim;
- Lee, Jae Yeol;
- ... Min, Sun-Joon;
- 외 1명
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42초록
A concise synthesis of tetrabenazine and dihydrotetrabenazine is described. The key feature of this synthesis is the intramolecular aza-Prins-type cyclization of an amino allylsilane via oxidative C-H activation.
키워드
VESICULAR MONOAMINE TRANSPORTER; CARBON BOND FORMATION; DIHYDROTETRABENAZINE; (+)-ALPHA-DIHYDROTETRABENAZINE; ALLYLSILANES; CATALYST; DISEASE; ESTERS; AGENT; DDQ
- 제목
- A Concise Synthesis of Tetrabenazine: An Intramolecular Aza-Prins-Type Cyclization via Oxidative C-H Activation
- 저자
- Son, Young Wook; Kwon, Tae Hui; Lee, Jae Kyun; Rae, Ae Nim; Lee, Jae Yeol; Cho, Yong Seo; Min, Sun-Joon
- 발행일
- 2011-12
- 유형
- Article
- 저널명
- Organic Letters
- 권
- 13
- 호
- 24
- 페이지
- 6500 ~ 6503
- 언어
- ENG
- 출판사
- AMER CHEMICAL SOC
- 발행국가
- 미국
- 분량
- 4 페이지
- ISSN
- E 1523-7052
P 1523-7060