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Global Phylogeny of Shigella sonnei Strains from Limited Single Nucleotide Polymorphisms (SNPs) and Development of a Rapid and Cost-Effective SNP-Typing Scheme for Strain Identification by High-Resolution Melting Analysis
- Sangal, Vartul;
- Holt, Kathryn E.;
- Yuan, Jianfeng;
- Brown, Derek J.;
- Filliol-Toutain, Ingrid;
- ... Kim, Dong-Wook;
- 외 6명
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17초록
The current Shigella sonnei pandemic involves geographically associated, multidrug-resistant clones. This study has demonstrated that S. sonnei phylogeny can be accurately defined with limited single nucleotide polymorphisms (SNPs). By typing 6 informative SNPs using a high-resolution melting (HRM) assay, major S. sonnei lineages/sublineages can be identified as defined by whole-genome variation.
키워드
KOREA; ANTIMICROBIAL RESISTANCE; ANTIMICROBIAL RESISTANCE; KOREA
- 제목
- Global Phylogeny of Shigella sonnei Strains from Limited Single Nucleotide Polymorphisms (SNPs) and Development of a Rapid and Cost-Effective SNP-Typing Scheme for Strain Identification by High-Resolution Melting Analysis
- 저자
- Sangal, Vartul; Holt, Kathryn E.; Yuan, Jianfeng; Brown, Derek J.; Filliol-Toutain, Ingrid; Weill, Francois-Xavier; Kim, Dong-Wook; da Silveira, Wanderley Dias; Pickard, Derek; Thomson, Nicholas R.; Parkhill, Julian; Yu, Jun
- 발행일
- 2013-01
- 유형
- Article
- 권
- 51
- 호
- 1
- 페이지
- 303 ~ 305
- 언어
- ENG
- 출판사
- AMER SOC MICROBIOLOGY
- 발행국가
- 미국
- 분량
- 3 페이지
- ISSN
- P 0095-1137