A Luciferase/Single-Walled Carbon Nanotube Conjugate for Near-Infrared Fluorescent Detection of Cellular ATP

  • Kim, Jong-Ho; 
  • Ahn, Jin-Ho; 
  • Barone, Paul W.; 
  • Jin, Hong; 
  • Zhang, Jingqing; 
  • 외 2명
Citations

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89
Citations

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100

초록

Take the tube: The title conjugate provides spatiotemporal information of ATP in living cells by a two-step fluorescence quenching mechanism. OxyLrin, which is generated enzymatically in the reaction between ATP and D-luciferin (Lrin), is adsorbed onto the nanotubes and quenches their fluorescence (see picture). The sensor is highly selective toward ATP.

키워드

ATP; biosensors; nanotechnology; nanotubes; near-infrared fluorescence; SINGLECELLSSELECTIVITYSENSORS
제목
A Luciferase/Single-Walled Carbon Nanotube Conjugate for Near-Infrared Fluorescent Detection of Cellular ATP
저자
Kim, Jong-Ho; Ahn, Jin-Ho; Barone, Paul W.; Jin, Hong; Zhang, Jingqing; Heller, Daniel A.; Strano, Michael S.
DOI
10.1002/anie.200906251
발행일
2010-02
유형
Article
저널명
Angewandte Chemie International Edition
권
49
호
8
페이지
1456 ~ 1459