Adenosine kinase attenuates cardiomyocyte microtubule stabilization and protects against pressure overload-induced hypertrophy and LV dysfunction

  • Fassett, John; 
  • Xu, Xin; 
  • Kwak, Dongmin; 
  • Zhu, Guangshuo; 
  • Fassett, Erin K.; 
  • 외 5명
Citations

WEB OF SCIENCE

27
Citations

SCOPUS

27

초록

United States Department of Health & Human Services-National Institutes of Health (NIH) - USA[-NIH National Heart Lung & Blood Institute (NHLBI)[HL20598,HL21872,HL71790];American Heart Association;Austrian Science Fund (FWF)[P 31083-B34];United States Department of Health & Human Services- National Institutes of Health (NIH) - USA-NIH National Heart Lung & Blood Institute (NHLBI)[R01HL139797]

키워드

Adenosine; Adenosine kinase; Cardiac hypertrophy; Detyrosinated tubulin; Microtubules; 2 chloroadenosine; adenosine kinase; adenosine phosphate; atrial natriuretic factor; mammalian target of rapamycin complex 1; mitogen activated protein kinase; myosin heavy chain beta; adenosine kinase; hydroxymethylglutaryl coenzyme A reductase kinase; adaptation; animal cell; aortic constriction; Article; attenuation; cardiac muscle cell; cell disruption; controlled study; detyrosination; disease exacerbation; disease marker; enzyme activity; enzyme regulation; fibrosis; heart function; heart left ventricle ejection fraction; heart left ventricle failure; heart left ventricle function; heart left ventricle hypertrophy; heart left ventricle overload; heart muscle metabolism; heart protection; heart stress; heart ventricle hypertrophy; homeostasis; immunohistochemistry; in vivo study; knockout mouse; lung congestion; male; membrane stabilization; microtubule; mouse; newborn; nonhuman; nucleic acid metabolism; priority journal; protein expression; protein methylation; protein modification; protein stability; rat; signal transduction; stress; wild type mouse; animal; cardiac muscle cell; cardiomegaly; genetics; heart stroke volume; MAPK signaling; metabolism; microtubule; pathology; pathophysiology; Sprague Dawley rat; Adenosine Kinase; AMP-Activated Protein Kinases; Animals; Cardiomegaly; MAP Kinase Signaling System; Mice; Mice, Knockout; Microtubules; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Stroke Volume; Ventricular Dysfunction, Left
제목
Adenosine kinase attenuates cardiomyocyte microtubule stabilization and protects against pressure overload-induced hypertrophy and LV dysfunction
저자
Fassett, John; Xu, Xin; Kwak, Dongmin; Zhu, Guangshuo; Fassett, Erin K.; Zhang, Ping; Wang, Huan; Mayer, Bernd; Bache, Robert J.; Chen, Yingjie
DOI
10.1016/j.yjmcc.2019.03.015
발행일
2019-05
유형
Article
저널명
Journal of Molecular and Cellular Cardiology
권
130
페이지
49 ~ 58

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