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Pyridoxine-derived bicyclic aminopyridinol antioxidants: synthesis and their antioxidant activities
- Nam, Tae-gyu;
- Ku, Jin-Mo;
- Rector, Christopher L.;
- Choi, Hoyoung;
- Porter, Ned A.;
- 외 1명
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15초록
A few facile synthetic pathways for bicyclic aminopyridinol antioxidants are presented. Attachment of a long alkyl chain to the bicyclic pyridinol scaffold was established using ester linkage. Non-substituted pyrrolopyridinols and 1,3-oxazine-fused pyridinols were also synthesized as novel antioxidant scaffolds. Antioxidant activities were measured by a radical clock method and new compounds prepared are comparable to the best bicyclic aminopyridinol antioxidants.
키워드
VITAMIN-E; BREAKING PYRIDINOL ANTIOXIDANTS; AUTOXIDATION; ANALOGS; BIOLOGICAL MOLECULES; REACTIVITY; ALPHA-TOCOPHEROL; 6-AMINO-3-PYRIDINOLS; RADICALS; PEROXIDATION; BREAKING PYRIDINOL ANTIOXIDANTS; ALPHA-TOCOPHEROL; VITAMIN-E; BIOLOGICAL MOLECULES; 6-AMINO-3-PYRIDINOLS; AUTOXIDATION; PEROXIDATION; REACTIVITY; RADICALS; ANALOGS
- 제목
- Pyridoxine-derived bicyclic aminopyridinol antioxidants: synthesis and their antioxidant activities
- 저자
- Nam, Tae-gyu; Ku, Jin-Mo; Rector, Christopher L.; Choi, Hoyoung; Porter, Ned A.; Jeong, Byeong-Seon
- 발행일
- 2011-09
- 유형
- Article
- 권
- 9
- 호
- 24
- 페이지
- 8475 ~ 8482
- 언어
- ENG
- 출판사
- ROYAL SOC CHEMISTRY
- 발행국가
- 영국
- 분량
- 8 페이지
- ISSN
- P 1477-0520