Microfluidic Chips for Immunoassays

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131
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150

초록

The use of microfluidic chips for immunoassays has been extensively explored in recent years. The combination of immunoassays and microfluidics affords a promising platform for multiple, sensitive, and automatic point-of-care (POC) diagnostics. In this review, we focus on the description of recent achievements in microfluidic chips for immunoassays categorized by their detection method. Following a brief introduction to the basic principles of each detection method, we examine current microfluidic immunosensor detection systems in detail. We also highlight interesting strategies for sensitive immunosensing configurations, multiplexed analysis, and POC diagnostics in microfluidic immunosensors.

키워드

immunosensor; microfluidics; multiplexed analysis; biochip; point of care; ENHANCED RAMAN-SCATTERING; LABEL-FREE DETECTION; ELECTROCHEMICAL DETECTION; ELECTRICAL DETECTION; MULTIPLEXED IMMUNOASSAY; CARBON NANOTUBES; MICROCHIP DEVICE; CARDIAC MARKERS; ANTIGEN PSA; SURFACE
제목
Microfluidic Chips for Immunoassays
저자
Han, Kwi Nam; Li, Cheng Ai; Seong, Gi Hun
DOI
10.1146/annurev-anchem-062012-092616
발행일
2013-03
유형
Article; Book Chapter
저널명
Annual Review of Analytical Chemistry
권
6
페이지
119 ~ 141