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In vitro Evaluation of Carbon-Based Nanospheres as Drug Delivery Vesicles in Breast Cancer Cell
- Kim, Daehyun;
- Kyung, Hyuna;
- Lee, Seung Soo;
- Park, So Yeon;
- Yoo, Won Cheol;
- 외 1명
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2초록
The application of nanoparticles in cancer treatment allows precise tumor treatment by enhancing drug delivery to the tumor area. To overcome limitations in the drug delivery system, we report carbon-based nanospheres (CSs) that have high drug loading capacity as well as anti-cancer effects. Monodisperse and size-tunable (170-583 nm) CSs with excellent surface area up to 2619 m(2)/g provided high drug loading capacity in four different types of drugs (doxorubicin, gemcitabine, docetaxel, and paclitaxel), and demonstrated strong anti-cancer effects against MDA-MB-231 human breast carcinoma cells.
키워드
Carbon nanosphere; Drug-delivery; In-vitro study; Cytotoxicity; NANOPARTICLES; SPHERES
- 제목
- In vitro Evaluation of Carbon-Based Nanospheres as Drug Delivery Vesicles in Breast Cancer Cell
- 저자
- Kim, Daehyun; Kyung, Hyuna; Lee, Seung Soo; Park, So Yeon; Yoo, Won Cheol; Lee, Hak Jong
- 발행일
- 2020-02
- 유형
- Article
- 권
- 41
- 호
- 2
- 페이지
- 112 ~ 116
- 언어
- ENG
- 출판사
- WILEY-V C H VERLAG GMBH
- 발행국가
- 독일
- 분량
- 5 페이지
- ISSN
- P 1229-5949