Glucose-Neopentyl Glycol (GNG) amphiphiles for membrane protein study

  • Chae, Pil Seok; 
  • Rana, Rohini R.; 
  • Gotfryd, Kamil; 
  • Rasmussen, Soren G. F.; 
  • Kruse, Andrew C.; 
  • 외 10명
Citations

WEB OF SCIENCE

82
Citations

SCOPUS

84

초록

The development of a new class of surfactants for membrane protein manipulation, "GNG amphiphiles", is reported. These amphiphiles display promising behavior for membrane proteins, as demonstrated recently by the high resolution structure of a sodium-pumping pyrophosphatase reported by Kellosalo et al. (Science, 2012, 337, 473).

키워드

FACIAL AMPHIPHILES; DETERGENT; STABILIZATION; RECEPTOR; SOLUBILIZATION; CRYSTALLIZATION; SURFACTANTS; STABILITY; PEPTIDE
제목
Glucose-Neopentyl Glycol (GNG) amphiphiles for membrane protein study
저자
Chae, Pil Seok; Rana, Rohini R.; Gotfryd, Kamil; Rasmussen, Soren G. F.; Kruse, Andrew C.; Cho, Kyung Ho; Capaldi, Stefano; Carlsson, Emil; Kobilka, Brian; Loland, Claus J.; Gether, Ulrik; Banerjee, Surajit; Byrne, Bernadette; Lee, John K.; Gellman, Samuel H.
DOI
10.1039/c2cc36844g
발행일
2013-02
유형
Article
저널명
Chemical Communications
권
49
호
23
페이지
2287 ~ 2289